Chem 332

Spring 2005
Lecture MWF, 10:10-11 AM in 101 Brown Labs

Professor Joseph M. Fox
272 Brown Labs
302-831-0191
jmfox@udel.edu

<>Office hours: Mondays 11-12, or by appointment.  Contact me by email to schedule an appointment.

The TA's for Chem 334 (Tom Daniel, Peter DeMatteo, Jeff Zheng, and Rebecca Mason) will also hold office hours

New Additions

A link to the lecture on solid phase synthesis and sugar chemitry has been added: see links and resources below.

Note:  This syllabus will be updated weekly— check it frequently.  Reading assignments will be added,  homeworks and answer keys will be linked. Prof. Taber's course page from previous years will be an important resource for old practice exams, homeworks, etc.
 

Textbooks:

Organic Chemistry, Vollhardt and Schore, 4th Edition
Organic Chemistry Study Guide, Schore
Organic Chemistry Laboratory, Third Edition by Bell, Clark and Taber
A Molecular Model Set is also required

<>Links and resources:

Chem 334  Laboratory course that accompanies Chem 332
Chem  332 from Spring 2003: resource for old problems
<> Prof. Taber's course page: resource for old problems
polymer lecture
Handout on IR
Handout on Mass Spec
Handout on Solid Phase Synthesis and Sugar Chemistry

Grading

There will be three hour exams and a final.  All of the exams will be weighted equally.  All exams will be open book, open notes.  Molecular models are also allowed during exams.

<>Weekly homework assignments will be collected.  


Honors  SectionThe Honors discussion group meets from 9:10-10:00 on Friday mornings to discuss topics from the primary chemical literature.  
<>
 

Problem Sets:  1   2   3   4   5   6   7   8   9   10
Problem Set Answers:  1   2   3   4   5   6   7   8   9   10
Exams:  1   2   3   4   
Exam Answers:  1   2   3   4   


<>Syllabus:
 

Week 1: First Class on Feb 9.  Instructions for indepedent study (of chem 334).   Chp.21 - Amines

Week 2: (Monday February 14th) Chp. 17, 18 - Aldehydes and Ketones
 

Week 3: (Monday Febuary 21).  Ring-forming Reactions: .
607-612, Chp. 19, 20, 23 Carboxylic Acids, Dicarbonyl Compounds.
 

Week 4:  (Monday Feb 28)   Ring-forming Reactions continued: Intramolecular aldol condensation (pg 785-787), Robinson annulation (pg 795-796), Dieckmann (pg 1028)
 
 

Week 5: (Monday March 7th).  Review for exam 1.  Exam 1 on Wed March 9th.  Sigmatropic (electrocyclic) Rearrangements, pg 596- 602; pg 581. 
 

<>Week 6: (Monday March 14h)   Diels-Alder  591-596.  Photochemical 2+2 additions to make 4 membered rings.  Carbenes to make 3 membered rings. pp. 496-498   Chp. 15, 16 Chp. 22 Aromaticity; Benzene Substitution.

 

Week 7: (Monday March 21st) Chp. 15, 16 Electrophilic Aromatic Substitution
Diazonium Salts  Aromaticity continued.  Lab Exam 1 on Monday March 21st
 
SPRING BREAK

Week 8: (Monday April 4th)  Chemistry of Benzene derivatives, Nucleophilic Aromatic Substitution 
 

<>Week 9: (Monday April 11sh) Review for exam 1.   Exam 2 on Wed April 13th.  Synthesis applications
   

Week 10: (Monday April 18th)  arrow-pushing mechanisms, organic polymers

Week 11: (Monday April 25)  Chp. 12, Chp. 26 Amino Acids, Peptides
 

Week 12: (Monday, May 2th)  Chp. 24 Sugars, Chp. 25 Heterocycles, Chp. 26 DNA, RNA
Lab Exam 2 on Monday May 2nd
 

Week 13: (Monday May 11th)  Review for exam 3.  Exam 3 on Wed May 11th 

 
Week 14: (Monday May 16th)   arrow-pushing mechanisms, synthesis, Review for final

Bring your questions to the last class Wed. May 18th
 

FINAL EXAM: TBA