Experienced and creative scientist with strong publication record, multidisciplinary background, and excellent buisness acumen seeks a rewarding position in a progressive, interdisciplinary environment.
Taber, D. F., Meagley, R. P. and Doren, D. J."Cyclohexenone Construction by Intramolecular Alkylidene C-H Insertion: Synthesis of (+)-Cassiol" J. Org. Chem. (in press)
Taber, D. F. and Meagley, R. P. "Diastereoselectivity in Uncatalyzed Intramolecular C-H Insertion by an Alkylidene Carbene" Tetrahedron Letters 1994, 35, 7909
Taber, D. F., Sahli, A., Yu, H., Meagley, R. P. "Efficient Intramolecular C-H Insertion by an Alkylidene Carbene Generated from a Vinyl Chloride" J. Org. Chem., 1995, 60, 6571
Taber, D. F., Walter, R. and Meagley, R. P. "Intramolecular C-H Insertion by an Alkylidene Carbene: Diastereoselective Synthesis of a Taxol A Ring Synthon", J. Org. Chem., 1994, 59, 6014
Taber, D. F. and Meagley, R. P. "A Colorful Grignard Reaction" J. Chem. Educ. (in press)
Taber, D. F. and Meagley, R. P. "Synthesis of 2-Chloroethyl (13C)-Methyl Sulphide" J. Radiolabled Compounds and Radiopharmaceuticals 1992, 11, 849
1081 Warren Rd. Apt. 3
Ithaca NY 14850
Phone: 607.255.7007
E-mail: rpm9@cornell.edu
May 1996 to present Cornell University, Ithaca NY. Postdocroral Associate. Designed new polymers for application to deep UV photomicrolithograpy. Synthesised novel nonomers and explored polymerization mechanisms.
February 1991 to May 1996 University of Delaware, Newark, DE. Doctoral Candidate. Discovered new methodology for enantioselective generation of quaternary centers applied to the total synthesis of asymmetric pharmaceuticals. Created prototypical bridged carboxylate rhodium catalyst for asymmetric carbene insertion catalysis based on mathematical model. Supervised research assistants. Consultant for networking and interfacing. Instituted environmentally benign protocols. Implemented cost cutting strategies. Elected safety and PR representative. Honored as top graduate in 1996 and best instructor 1993.
February 1990 to February 1991 E. I. Du Pont De Nemours and Co. Experimental Station, Wilmington, DE. Chemist in CR&D department investigating the synthesis of fluorinated compounds with unusual properties. Developed spectroscopic method for polarity determination. Effected purification of complex mixtures achieving full characterization of components.
November 1989 to February 1990 Johnson Matthey Inc. W. Deptford, NJ. Process Development Chemist, Biomedical division. Synthesized a wide variety of pharmaceutical products and optimized fractional gram reactions to kilogram scale. As several of these were potent C.N.S. active agents, and intermediates possess acute toxicity, excellent technique was required. Ensured that products met U.S.P.
June 1989 to Nov. 1989 E. I. Du Pont De Nemours and Co., Newark, DE. Research Technologist, CR&D department. Applied photomicrolithographic techniques to superconductive thin films. Engineered molecular beam epitaxy apparatus. Invented new substrate processing scheme and implemented rigorous purity control to effect a dramatic increase in device performance.
March 1989 to June 1989 GEOMET, Rockville, MD. Instrumentation Specialist Executed study of passenger aircraft environment for congressional review. Responsible for data collection, supervised field calibration and repairs of all instruments.
May 1996-Present Cornell University, Ithaca NY. Postdoctoral Associate under the direction of Prof. Jean M. J. Frechet. Developed new photopolymer resist technology for deep UV application. Invented new strategies for radical and anionic polymerization.
Feb. 1991-May 1996 University of Delaware, Newark DE. Ph.D. in Organic Synthesis. GPA 3.8, Dissertation on alkylidene carbene C-H insertion reactions in the synthesis of important physiologically active natural products Taxol and Cassiol, under Prof. Douglass F. Taber. Achieving eight publications (reprints available upon request). Delivered annual presentations at professional meetings. Representative on safety and public relations committees. Honored as top graduate with the 1996 Glenn S. Skinner Memorial Prize and the 1993 Elizabeth Dyer Award for teaching excellence.
1985-1988 University of Maryland, College Park, MD. B.S. in chemistry awarded 12/01/88. Research under Dr. James Herndon investigating copper mediated coupling reactions.
1983-1984 Frederick Community College, Frederick, MD
Business- Managed sales accounts for construction contracts, light equipment and consumer electronics. Accounting and inventory control. Performed cost/benefit analysis for capital expenditures
Research- Scouted new areas for scientific inquiry and expedited transfer of technology to development team. Established new protocols for safety, solvent recovery and waste management. Supervised undergraduate and graduate assistants in independent research as well as in a team environment.
Natural Products- Synthesized cassiol & taxol synthon. Expert design and execution of asymmetric multi-step syntheses.
Pharmaceuticals- pilot scale synthesis of pharmaceutical products for human consumption. U.S.P. analysis. D.E.A. accounting
Polymers- Conducted research on Conducted postdoctoral research on deep UV photopolymers for photomicrolithography & industrial research on fluorinated monomer synthesis and polymerization.
Electronic- Design, calibration and repair of precision instruments. Power supply, audio and rf circuit design. Fiber optics and lasers.
Mechanical- light equipment design and fabrication. Laboratory glassware design. Proficient with most tools.
HPLC/IPLC- instructor, methods development, instrument design
"Wet" methods- U. S. P. assay, analytical chemistry instructor
High Field NMR- expert Bruker FTNMR (400, 300 & 250 MHz)
Published- catalyst design via semi-empirical methods. Transition state and relative energy calculations on organic and organometallicmolecules (ZINDO, Huckel, MOPAC).
Consulting- networked systems and interfacing. Hardware and software purchasing. System configuration, upgrades.
Professor Jean M. J. Frechet, Department of Chemistry, Cornell University, Ithaca, NY 14853-1301, (607) 255-1183
Professor Douglass F. Taber, Department of Chemistry and Biochemistry, University of Delaware Newark, DE 19716, (302) 831-2433
Professor H. Keith Chenault, Department of Chemistry and Biochemistry, University of Delaware Newark, DE 19716, (302) 831-1072
Dr. Carl G. Krespan, Senior Research Fellow, Central Research and Development, E. I. Du Pont De Nemours and Co. Experimental Station, Wilmington, DE 19880-0328, (302) 695-1200