Delaware NIH-INBRE grant supports cancer, cardiovascular, neuroscience research
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10:01 a.m., April 28, 2009----Fifteen developmental research projects, selected through a competitive, peer-review process, will be supported in the first year of Delaware's INBRE renewal program, which is funded by a five-year, $17.4-million grant from the National Center for Research Resources at the National Institutes of Health (NIH). The grant begins May 1.

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These projects, to be undertaken by academic and clinical researchers across the state, are aimed at generating preliminary data to support the development of subsequent research proposals to NIH, as well as other potential funding agencies.

Cancer Research:

--Autocrine Stimulation of Primary and Metastatic Brain Cancer Cells - Deni Galileo, University of Delaware
--Interactive Computer-generated Diagnosis Tools for Ground-glass Opacity Lung Tumors - Chandra Kambhamettu, University of Delaware
--Volumetric Breast Density Estimation using Breast Surface Reconstructed from Optical Digitizer Images - Fengshan Liu, Delaware State University
--Direct Interaction of Eristostatin with Human Melanoma Cells - Mary Ann McLane, University of Delaware
--Calcium- and Integrin-Binding Protein 1 (CIB1) in Cancer Cell Invasion - Krishna Sarker, University of Delaware
--CXCR4 and P-glycoprotein in Neuroblastoma Metastasis - Cynthia van Golen, Delaware State University
--DNA Damage Repair/Tolerance and Human Cancer - Zhihao Zhuang, University of Delaware

Cardiovascular Research:

--Biomaterials for Cardiac Tissue Engineering - Robert Akins, Nemours
--Endothelial Progenitor Cell Function in Chronic Kidney Disease - David Edwards, University of Delaware
--Physiological Effects of Dietary Sodium in "Salt Resistant" Humans - William Farquhar, University of Delaware
--Effect of Kidney Function on the Association Between Obesity and Cardiovascular Events - Claudine Jurkovitz, Christiana Care Health System

Neurosciences Research:

--Molecular Mechanisms of Learning and Memory: Investigating the Role of DEL-4 - Harbinder Dhillon, Delaware State University
--Systematic Analyses of SMN Complexes in Motor Neurons - Ilsa Gomez-Curet, Nemours
--Effect of Renin Inhibition on Cardiovascular Autonomic Nerve Function in Diabetes - Raelene Maser, University of Delaware
--Neuro-Cognitive Self Regulation Mechanisms and Their Relation to Childhood and Adult Obesity - Steven Most, University of Delaware