Tentative Schedule

The class meets Monday, Wednesday, and Friday from 9:05 to 9:55 AM in 205 Brown Laboratory.


August 27
Intro. and Review of Metabolic Principles

August 29
Form Groups, Group work on metabolic reactions involving pyruvate.
September 1
Labor Day - Holiday
September 3
ATP and Bioenergetics   
Energy Charge, and Adenylate Metabolism.
September 5
Inborn Errors of Metabolism - Assignment due
Review of Pyruvate Pyruvate metabolism, Pyruvate dehydrogenase and its coenzymes
September 8
Adenylate Kinase and Adenylate Energy Charge
Aspects of Metabolic regulation by Adenylates
Homing in on Catabolism of Lipid, Carbohydrates, and Proteins
September 10
Lactose structure and metabolism
Pentose Phosphate Pathway 
NAD vs NADP in Redox Reactions

September 12
Review of Carbohydrate Metabolism
- Problems due

Life Without Oxygen problem for groups in class
Page 1, 2,

September 15
Life Without Oxygen problem, 2a, 2b
Go over Homework Problem set 2
September 17
Life Without Oxygen problem, 3, Summary
Are you what you eat?  Page 1
Read text chapter on Photosynthesis for Friday
Calvin-Benson Cycle Intermediates-cutout
September 19
Calvin Cycle
Are you what you eat? Pages 2a & b
September 22
Are you what you eat? Page 3 & 4
September 24
Are you what you eat? Page 5
September 26
Concluding Discussions, Summary
September 29
Group quiz on Glycolysis and Photosynthesis

October 1
Intro to Fatty Acid Structure and Nomenclature
Fatty acid oxidation
Fatty Acid Synthesis vs Degradation
Coenzyme A structure and function
October 3
Ketone Body Metabolism
Propionyl CoA Metabolism
Coenzyme B12
Lipid Metabolism - Problems  due
October 6
Citrate-pyruvate Cycle
Glyceride Metabolism
October 8
Steroid and Isoprenoid Biosynthesis
Overview of Isoprenoid metabolism
HMG-CoA and IPP synthesis
October 10
Rxns of HMGCoA - Problem due
Wrap up lipid metabolism
The Nitrogen Cycle
Intorduction to nitrogen fixation
October 13
Conceptual Class Activity on Modular assembly and self assembly in biosynthesis
October 15
Nitrate and Nitrite Reduction
Intro. Amino Acid Metabolism
Nitrogen Acquisition and Excretion
October 17
Lysine Biosynthesis - Problem due
Ammonium entry into metabolism
Glutamine Synthetase and its Regulation
Pyridoxal Phosphate (PLP)
October 20
Glutamate Family of Amino Acids
Synthesis of Proline from Glutamate
Synthesis of Arginine from Glutamate via Ornithine 
October 22
Flux in Metabolism
Oxaloacetate Family of Amino Acids
Regulation of Branched Biosynthetic Pathways
October 24
Biosynthesis of Essential Amino Acids - due
Generation of Formyl and Methyl Groups-
Folate Metabolism
Urea Cycle
Amino Acid Catabolism
October 27
Creatine Creates Controversy p1-5
October 29
Sick Kids with an Unusual Organic Aciduria p1, p2, Summary
October 31
Human Starvation
Metabolic Limits of Human Performance
November 3
Midterm Exam, (examinations for the past 10 years posted on course home page.) 8:00 am - 10 am
November 5
Review of Examination

November 7
Plant vs Animals in the Dining Hall.  Page 1
November 10
Plant vs Animals in the Dining Hall.  Page 2
November 12
Plant vs Animals in the Dining Hall   Page 3
November 14
Plant vs Animals in the Dining Hall. Page 4, Page 5, and Summary

November 17
Begin Final Group Project
November 19
Group Project
November 21
Group Project
November 24
Group Project
November 26
Thanksgiving Break
November 28
Thanksgiving Break
December 1
Group Project due
Group Project Preparation
December 3
Group Project Presentations
On-line course evaluations due
Review session Tuesday, December 9, 2014, 2:00-4:00 PM in 205 Brown Lab.
Final Exam  (examinations for the past 10 years posted on course home page.)

Wednesday, December 10, 2014, 3:30-6:30 PM in 205 Brown Lab.

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Last updated  12 December 2014 by Hal White. (halwhite at
Copyright 2014, Harold B. White, Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716