Delaware Chapter, ASA

Dinner Meeting: March 2010

See meeting photos


Meeting location: Courtyard Marriott located close to Willard Hall Conference Center on the University of Delaware Laird Campus. Marriott Courtyard

Speaker:   Zhaohui (John) Cai, MD, PhD
Director of Biomedical Informatics AZ
Title:   Personalized Medicine and Model-based Drug Development: Opportunities for Biomedical Informatics.


Zhaohui Cai, MD, PhD, will discuss the potentials of biomedical informatics in enabling personalized medicine in clinical drug development with real case scenarios. Personalized medicine seems to be based on the recognition that unprecedented types of information will be obtainable by the application of genetic, genomic, proteomic, imaging, etc, technologies, which will help us further refine known diseases into unknown categories. In drug development, personalized medicine has promised to stratify patient populations based on treatment effectiveness and safety, and therefore deliver more targeted therapies and safer medicines.

However, the wide application of the new technologies to clinical trials has not come to reality in the pharmaceutical industry for all kinds of reasons, such as limitations in trial designs, extra cost and time, and uncertainly in regulatory and commercial consequences. This presentation will focus on a reasonable step we are taking, which is modeling and simulation using currently available clinical data from historical and early phase clinical trials to enable patient stratification and novel designs in late phase clinical trials, without applying any new technologies. Real examples of modeling applied to drug projects will be illustrated and the value of such a practical approach will be discussed.


Zhaohui (John) Cai, PhD is a Director at AstraZeneca supporting Therapeutic Areas and Patient Safety in Clinical Development. He received his MD from China Medical University, PhD from Albany Medical College, and Biomedical Informatics Fellowship training from Harvard Medical School. At AstraZeneca, John is also the US region coordinator of modeling and simulation in Statistics and Informatics. He has been involved in data mining, text mining, as well as providing modeling support to drug projects and safety knowledge groups.

Date: Thursday, March 18, 2010

Social time -- 6:00 pm
Seated/order -- 6:20 pm
Dinner -- 6:45 pm
Speaker -- 7:20 pm

Courtyard by Marriott, Newark University of Delaware
400 Pencader Way
Newark, DE   Directions/Map

Note: Please bring cash to streamline the logistics. Thanks.

All sandwiches come with your choice of any one of our special spuds or sides. French fries, Old Bay Fries, Garlic Butter Fries, Baked Potato, side salad, Vegetable of the day, Chips or a Fruit Salad. Add a bowl of hearty soup for $3.50.


  • Durango Chicken Sandwich $9.95: Breast of chicken, our Sweet Baby Ray's BBQ sauce, melted cheese, tomatoes, and a pile of thick bacon on a brioche roll. Of course we plate it up with our tasty, golden fries.

  • Salmon Cake $9.95: Eight ounces of fresh Atlantic salmon cake, full of Omega 3, spring greens, thinly sliced red onions and tomato, on a brioche roll with a side of bayou mayo.

  • The Newark Harvest $10.95: A mix of young Mesclun field greens, local Milburn Orchard apples, brandied cranberries, blue cheese crumbles and healthy walnuts in a light raspberry vinaigrette. Add chicken, grilled shrimp or a 6 oz salmon filet for $4.95

  • Jumbo Lump Crab cake: $12.95 : Jumbo Lump Crabmeat, NO Fillers, pan-seared until golden brown Served with a Creole-style mustard sauce.


Cost: $10 for members/others, students $5 (plus dinner)
Reservations to: 

Irina Baldytcheva by Wednesday, March 17, 2010.
Phone: 302-885-9136
Email: Irina Baldytcheva.

Please note: Be sure to RSVP by this date.

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