60
INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE
UNIVERSITY OF DELAWARE

CONTINUING REVIEW FORM
(Revised June 22, 2000)

IACUC approval of animal protocols must be renewed on an annual basis.  Please complete this form, beginning with Record of Animal Usage, for the protocol identified below.

Protocol title	Electrophysiological Recording from Fish Brain	 		

Animal use protocol (AUP) number    

Principal Investigator	David P.M. Northmore

Department: Psychology	

Previous approval date	: July 2001

 Project category				

IACUC Approval Signature                                                    Date                             

New AUP number:                                            	

1.	RECORD OF ANIMAL USAGE

       Species	
 Total number approved 	
 Number used to date	

Carassius auratus (Goldfish)	450
	120

Lepomis macrochirus (Sunfish)
	50
	23

	

2.	PROTOCOL STATUS.  Please indicate (X) the status of this project.
Request Protocol Continuance

A.	_x__ Active--project ongoing

B.  ___ 	Currently inactive--project was initiated but is presently inactive.

C.  ___ 	Inactive--project never initiated but anticipated start date is_________________.

Request Protocol Termination

D.  ___	Inactive--project never initiated

E.  ___	Completed--no further activities with animals will be done.

3.	FUNDING SOURCE:  None currently

4.	PROJECT PERSONNEL:  Have there been any personnel changes since the last IACUC approval?

___ 	No	

_X__	Yes    If yes, complete the following sections (Additions/Deletions).  For additions, 		please attach a statement describing the training and qualifications of each individual 		added.

Additions:	Name/role/responsibility for project

 Shawn Gallagher will be leaving the University of Delaware in the Fall of 2003 and only working on the project in a part-time capacity.  Two undergraduate students, Vivek Prashant Patel                                                                                                                  

Deletions:	Name/effective date

                                                                                                                      

Attach current or new copies of the Animal Facility Safety Training Certification for all personnel who will have animal contact or will be working in the facility.

5.	PROGRESS REPORT.  If the status of this project is 2.A or 2.B, provide a brief update on the 	progress made in achieving the aims of the protocol.

6.	PROBLEMS/ADVERSE EVENTS.  If the status of this project is 2.A or 2.B, describe any unanticipated adverse events, morbidity, or mortality, the cause if known, and how these problems were resolved.  If NONE, this should be indicated.

7.	ALTERNATIVES TO ANIMAL USE.  Alternatives to the use of animals should be considered and used when possible.  Since the last IACUC approval, have non-animal alternatives become available that could be substituted to achieve your project aims?  Provide a written narrative that addresses the above question and support your reply by conducting a literature search to determine that non-animal alternatives are not available.

Data bases such as Medline, Agricola, Index Medicus, Current Contents, Toxline, Biosis, etc., should be used.  The date of the search, the years covered by the search, and the keywords used for the search must be provided.  The IACUC requires that the keyword alternatives - be part of all searches.  (A list of resource organizations is included as an attachment.)

8.	ALTERNATIVES TO POTENTIALLY PAINFUL PROCEDURES.  If you have indicated by checking either box D or E under Section II of the original protocol submittal (Category of Research) that animals used in your proposed procedure(s) may experience more than momentary or slight pain and distress, you are required to perform a literature search to determine that alternatives are not available.  Alternatives may include substitution of non-animal methods or use of animals lower on the phylogenetic scale, reduction of the number of animals, or refinement of the proposed procedures.  Since the last IACUC approval, have potentially less painful or distressful alternatives become available that could be used to achieve your project aims?  Provide a written narrative that addresses the above question and support your reply by conducting the required literature search.

Data bases such as Medline, Agricola, Index Medicus, Current Contents, Toxline, Biosis, etc., should be used.  The date of the search, the years covered by the search, and the keywords used 	for the search must be provided.  The IACUC requires that the keyword alternatives- be part of all searches.  (A list of resource organizations is included as an attachment.)

9.	DUPLICATION.  Activities involving animals must not unnecessarily duplicate previous experiments. Provide a written narrative that assures that the activities of this project remain in compliance with this requirement and support this assurance by performing a literature search.

Data bases such as Medline, Agricola, Index Medicus, Current Contents, Toxline, Biosis, etc., should be used.  The date of the search, the years covered by the search, and the keywords used for the search must be provided.  The IACUC requires that keywords indicating the species and primary procedures, processes, or chemicals being studied be part of all searches.  (A list of resource organizations is included as an attachment.)

10.	FUTURE PLANS.

___	No changes are planned, and the project will continue as previously approved by the IACUC.

___	Changes are planned.  Provide a full description and justification for the proposed changes in the form of an amendment to the protocol.  If the modifications are significant, the IACUC may require a new application.  If you have questions, please contact the Research Office or the Attending Veterinarian.

___	Other.  Please explain.

CERTIFICATION OF THE PRINCIPAL INVESTIGATOR.  Signature certifies that the principal investigator understands the University of Delaware's regulations and policies for the use and care of laboratory animals for research, testing, teaching, or demonstration purposes.  Signature further certifies that the investigator will continue to conduct the project in full compliance with the aforementioned requirements.

                                                                                                                                  
Signature						Date

6/12/00

Appendix 1	FOR INFORMATION ONLY 
	DO NOT SUBMIT THIS PAGE!

	RESOURCE ORGANIZATIONS FOR ALTERNATIVES

Animal Welfare Information Center (AWIC)
National Agricultural Library Room 304
Beltsville, MD  20705
(301) 504-6212	FAX  (301) 504-5472

Institute for Laboratory Animal Resources (ILAR)
National Research Council
2101 Constitution Avenue
Washington, D.C.  20418
(202) 334-2590	FAX  (202) 334-1639

Johns Hopkins Center for Alternatives to Animal Testing (CAAT)
615 North Wolfe Street
Baltimore, MD  21205
(410) 955-3343	FAX  (410) 955-0258

National Institute of Health
National Library of Medicine
Bethesda, MD  20894
(301)  496-6095	FAX  (301) 496-4450

PRIM&R
132 Boylston Street, 4th Floor
Boston, MA  02116
(617) 423-4112	FAX  (617) 423-1185

Scientists Center for Animal Welfare (SCAW)
4805 St. Elmo Avenue
           Bethesda, MD  20814