Jerome Siegel
Professor 
Ph.D., Ohio State University, 1960
jsiegel@udel.edu
Department of Psychology
Phone: Office (302) 831-2936: Lab 831-8718: Fax
831-3645
Office: Room 216 Wolf Hall
Research Interests
I have been investigating the extra-thalamic diffuse projections to cortex
that regulate neural activity underlying sleep, waking, and other behaviors
in cats and rats. These subcortical systems and their neurotransmitters
include the noradrenergic locus coeruleus, dopaminergic ventral tegmental
area, serotonergic raphe nuclei, and the cholinergic basal forebrain. Currently
being studied are the roles of the above modulating systems in producing
augmenting and reducing of visual evoked potentials recorded from rat visual
cortex. We have shown that evoked potential augmenting and reducing is
correlated with sensation seeking behaviors in humans, cats, and rats.
These studies, using electrophysiological and pharmacological methods in
rats, are shedding light on the neural mechanisms (brain areas and neurotransmitters)
that determine sensation seeking, exploratory, risk taking, and addictive
behavior.
Recent Publications
-
Siegel, J., & Sisson, D. F. (1993). Evoked field potentials, beyond
correlates of behavior: An approach to determining the neural mechanisms
of behavior. In Slow Potential Changes in the Brain. W. Haschke,
E.-J. Speckmann, & A. I. Roitbak (Eds.). Birkhauser Boston, pp. 151-165.
-
Siegel, J., Sisson, D. F., & Driscoll, P. (1993). Augmenting and reducing
of visual evoked potentials in Roman high- and low-avoidance rats. Physiol.
Behav., 54:707-711.
-
Siegel, J., Gayle, D., Sharma, A., & Driscoll, P. (1996). The locus
of origin of augmenting and reducing of visual evoked potentials in rat
brain. Physiol. Behav., 60:287-291.
-
Siegel, J., & Driscoll, P. (1996). Recent developments in an animal
model of visual evoked potential augmenting/reducing and sensation seeking
behavior. Neuropsychobiol., 34:130-135.
-
Siegel, J. (1997). Augmenting and reducing of visual evoked potentials
in high and low sensation seeking humans, cats and rats. Behav. Genet.,
27:557-563.
-
Morton, C., Siegel, J., Xiao, H.-M., & Zimmerman, M. (1997). Modulation
of cutaneous nociceptor activity by electrical stimulation in the brain
stem does not inhibit the nociceptive excitation of dorsal horn neurons.
Pain, 71:65-70.
Return to:
Psychology Homepage