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DURHAM, N.C., Feb. 22 — A girl died today after two weeks in which she received the wrong heart and lungs in one transplant operation and then suffered brain damage and complications. 

The girl, Jésica Santillán, 17, a Mexican immigrant who came to America three years ago seeking medical treatment for a life-threatening heart condition, was declared dead at 1:25 p.m, her family's lawyer said. Her heart stopped at 5:07. Doctors removed her from a respirator at 5:10 p.m.

Ms. Santillán's case drew wide attention. Pictures of the girl, brown-eyed and smiling, adorned shops and restaurants. People worldwide sent greetings this month.

Dr. James Jaggers, the transplant surgeon who made the error, released a statement last night saying: "I am ultimately responsible for the team and for this error. 

Richard A. Puff, a spokesman for Duke, said in an interview after Jésica was removed from life support this evening that there was no second opinion given and none was refused. Mr. Puff said he could not confirm whether one was requested. He said hospital doctors and administrators were not available for comment.

Ms. Santillán had waited three years for the first transplant but a new set of organs was found within days, which her supporters attribute to publicity of her condition. A second operation with the organs of the correct blood type was performed Thursday but Ms. Santillán developed complications.

Ms. Santillán had been suffering almost since birth. She was born in Guadalajara, Mexico, to poor laborers. At age 12 she was found to have restrictive cardiomyopathy, a condition characterized by an enlarged and weakened heart and malfunctioning lungs. 

With the chance of a transplant in Mexico virtually impossible, they paid a smuggler to take them to the United States, through the desert and eventually to Durham, where relatives had said there were hospitals to help them.