CHEM-643
INTERMEDIARY METABOLISM
Tentative Schedule
FALL SEMESTER 2005

The class meets Monday, Wednesday, and Friday from 9:05 to 9:55 AM in 110 Memorial Hall.

Monday
Wednesday
Friday 

August 31
Intro. and Review of Metabolic Principles 
September 2
ATP and Bioenergetics   
September 5
Labor Day - Holiday 
September 7
Energy Charge, and Adenylate Metabolism. Group work on metabolic reactions involving pyruvate.
September 9

Inborn Errors of Metabolism - Assignment due
Review of Pyruvate Pyruvate metabolism, Pyruvate dehydrogenase and its coenzymes

September 12
Lactose structure and metabolism
Pentose Phosphate Pathway  (oxidative branch)
September 14
Pentose Phosphate Pathway  (non-oxidative branch) 
NAD vs NADP in Redox Reactions
Introduction to Fatty Acid Structure and Nomenclature

September 16
Review of Carbohydrate Metabolism
- Problems due

Triglycerides and Phospholipids
Sphingolipids
Oxidation of  Fatty Acids

September 19
Fatty acid oxidation
Propionyl CoA Metabolism 
Coenzyme B12
Biosynthesis of Lipids
September 21
Ketone Body Metabolism
Comparison of Fatty Acid Synthesis and Degradation
September 23
Lipid Metabolism - Problems  due
Case Study Project Topic due.


September 26
Citrate-pyruvate Cycle, Phosphoinositides
Principles of Self Organization
Glyceride Metabolism
September 28

Prostaglandins
Steroid and Isoprenoid Biosynthesis
Overview of Isoprenoid metabolism
HMG-CoA and IPP synthesis
 
September 30
Rxns of HMGCoA - Problem due
Intro. Amino Acid Metabolism
Nitrogen Acquisition and Excretion
Nitrogenase
Nitrate and Nitrite Reduction
Molybdopterin 

October 3
Ammonium entry into metabolism
Glutamine Synthetase and its Regulation
Pyridoxal Phosphate (PLP)
October 5
Glutamate Family of Amino Acids
Synthesis of Pro from Glutamate
Synthesis of Arg from Glu via Orn
October 7
No Class


October 10
Guest lecture by Dr Richard Hanson on "Principles of Intermediary Metabolism."

Biochemistry seminar by Dr. Richard Hanson at 4, "The Role of PEP Carboxylase in the Control of Energy Metabolism."
October 12


Lysine Biosynthesis in class
October 14
Biosynthesis of Essential Amino Acids - Problem due
Flux in Metabolism
Phosphoglycerate Family of Amino Oxaloacetate Family of Amino Acids Regulation of Branched Biosynthetic Pathways
October 17
Generation of Formyl and Methyl Groups-Folate Metabolism
Urea Cycle
Amino Acid Catabolism
October 19
  Nucleotide Structure and Metabolism
Purine Biosynthesis
Pyrimidine Biosynthesis
October 21
Deoxynucleotide biosynthesis
Purine Salvage Pathways
October 24
MidTerm Examination
October 26
Are you what you eat?  Page 1
Photosynthesis
October 28
Fall Break
No Class
October 31 
Are you what you eat?  Page 2
November 2
Are you what you eat? Page 3
November 4
Are you what you eat? Page 4
November 7
A discussion with Dr. Lane about his career and research interests.
Biochemistry Seminar by Dr. Daniel Lane at 4.
November 9
Are you what you eat?
 Page 5

November 11

Complete discussion of Case Study Problem 1 Summary
November 14

Individual and Group Quiz .
 
November 16
Folate Metabolism
Kellogg's
Product 19 Page 1  and 2
November 18
Kellogg's Product 19 Page 3
November 21
Work on Concept Map for Folate Metabolism Problem Page 4
November 23
Work on Concept Map for Folate Metabolism Problem
November 25
Thanksgiving Break
November  28
Amino acid Metabolism Case Study - Page 2
November 30
Concept Map Due.
Creatine Creates Controversy Case Study
December 2
Case Study/PBL Problem Due
December 5
Course Evaluations Due
Tuesday, Dec 7 by 4:30 PM
December 7
Last Day of class.
 
Final Exam
December 14, 3:30 - 6:30 PM


Return to Department's Home Page, CHEM-643 Home Page, CHEM-643 Syllabus, or Hal White's Home Page.
Last updated 20 November 2005 by Hal White. (halwhite at udel.edu)
Copyright 2005, Harold B. White, Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716