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Chem 635
Syllabus: Class will be meeting Tuesdays 7-10 in 207 BRL. Each week we will present and discuss
total syntheses, including talking about strategy, and reviewing reagents and
mechanisms. There will be two
exams and a final, each three hours.
The exams will be based on the reagents and mechanisms from the articles
that have been presented.
Remember, we may or may not have discussed those particular aspects of
the article in class.
Each
week, you will need to send me by Tuesday noon two articles on total synthesis,
in .pdf format, by email. I will
choose one, and you will write a report, 1-3 pages with pictures, summarizing
what you think is important about that article. This report, along with the .pdf of the article, are to be submitted to me by email by
noon on Thursday. You will select
the articles that you present from those on which you have written a
report. Any total synthesis
in JACS, JOC or
Angewandte Chemie is fair game.
From other journals, there is less of a chance of being acceptable, but
there are some good syntheses in
Org Lett, Tet Lett and other
journals.
In
your report, please focus on overall strategy. What problems did they have to solve, and how did they solve
them? What are the broader
implications/applications of those solutions?
Do
not resubmit an article that I have rejected once - if you send me two good
ones, I will tell you that, and you will be able to use the other one another
time.
Please read and think about the article that I will send you by the first Tuesday at 7:00, and remember - your first two articles
are due to me by that Tuesday at noon.
Exams: Exams will be March 24 and April 28. There will also be a final exam. All exams are open book and open notes.
For 2005 exams, see Exam #1 2005, Exam #2 2005, Exam #3 2005
For 2005 answers, see Exam #1 2005 key, Exam #2 2005 key, Exam #3 2005 key
For 2006 exams, see Exam #1 2006, Exam #2 2006, Exam #3 2006
For 2006 answers, see Exam #1 2006 key, Exam #2 2006 key, Exam #3 2006 key
For 2007 exams, see Exam #1 2007, Exam #2 2007, Exam #3 2007
For 2007 answers, see Exam #1 2007 key, Exam #2 2007 key, Exam #3 2007 key
For 2008 exams, see Exam #1 2008, Exam #2 2008, Exam #3 2008
For 2008 answers, see Exam #1 2008 key, Exam #2 2008 key, Exam #3 2008 key
For 2009 exams, see Exam #1 2009, Exam #2 2009, Exam #3 2009
For 2009 answers, see Exam #1 2009 key, Exam #2 2009 key, Exam #3 2009 key
Presentations: All presentations will be by PowerPoint. Please email to the class, and me, a .pdf of the article that you will be reviewing by 5 p.m. on the Wednesday (a week ahead!) before the presentation.
Questions and comments to Douglass
F. Taber