(1) Tyrosine is hydroxylated to L-DOPA by tyrosine hydroxylase.
 
 
 
 
 
 
 
 

(2) L-DOPA is decarboxylated to dopamine.
 
 
 
 
 
 

(3) A secondy hydroxylation yields norepinephrine.
 
 
 
 
 
 
 

(4) Methylation of norepinephrine’s amino group produces epinephrine.
 
 
 
 
 
 
 

[1]Voet, Donald and Voet, Judith. Biochemistry. 2^nd Edition. Pages 759-760