Two Problems Illustrating Genes and the Brain

Group #2: Matt Huenerfauth, Rishi Khan, and John Shackelford

     Neuroscientists have been plagued for some time as to which areas of the brain music actually stimulates. But at the Institute of Neurology in London, neuroscientist Richard Frackowiak is convinced that there is not of a single "music box" in the brain; research suggests that numerous parts of the brain are activated. Frackowiak took PET scans of several men's brains as they listened to four different tapes. There were thirty sequences of musical excerpts on each of four tapes; the first contained a change in timbre for half the songs, one tape contained a change in the pitch for half the songs, and another tape contained a change in the rhythm for half the songs. The fourth tape was only used to determine which type of music the subjects were familiar with.
     The results indicated that the music most familiar to the men stimulated the Broca's area located in the left hemisphere. The men reported that the familiar tunes also brought to mind their titles or at least a "brain search" for the title. This, in turn, was not surprising since Broca's area is also responsible for processing the cadences of spoken language. The change in timbre accounted for a stimulation of the right hemisphere, the only thing to account for an activation of the right hemisphere. The results of the change in pitch trial were the most surprising. The pitch variations activated the precuneus, a region on the left rear of the brain. Past studies have shown this region to be linked with visual imagery - possibly suggesting that you may visualize the rising and falling of a stave in your mind's eye. The study concluded that music is processed in the front and back of the brain in a more complex manner than previously believed.      For the past half-century, neuroscientists have postulated that the brain "works" in a manner similar to that in which a computer works. The foundation for this hypothesis stems from the fact that the brain is composed of billions of neurons wired in an elaborate manner. Likewise, a computer consists of millions of interlinked switches of minimal individual processing ability.
     Recent research has proven this model incorrect by showing that single neurons can actually perform intricate calculations and register fine discriminations. Also, the more a neuron is used, the stronger it becomes - an indication of a type of development not present in computers. Moreover, neurons have numerous electrically active components in the incoming branches. These branches are able to regulate the amount of incoming messages and distribute the messages to surrounding neurons depending on the strength of the synapse. This type of intelligent message management is much more sophisticated than that of any modern computer.
     In the past, researchers believed that the representation of information depended on overall rate of neuron firing over periods of time; however, it has recently been shown that some cells in monkeys' brains can adjust the rate of firing in individual increments as little as on hundredth of a second. This adjustment can cause a back-propagated neural spike that will strengthen the incoming branch of the neuron while suppressing random or unimportant messages.
     This research shows that the brain should now be viewed as a hybrid computer employing both digital pulses and analog computations. This study reaffirmed that human neural synapses are extremely complicated; Intel will not be creating a replacement for you brain in the near future.